Pyronaridine Tetraphosphate UVRAG is a mammalian ortholog of

2019-07-25

UVRAG is a mammalian ortholog of yeast Vps38 and a promoter of autophagy [51,60,61]. It forms distinct complexes with BECN1 (mammalian ortholog of yeast Vps30/Atg6) and the class III phosphatidylinositol 3-kinase (whose catalytic subunit [PIK3C3] is the mammalian ortholog of yeast Vps34) and contributes to both autophagosome formation and maturation [60,62].

Methods and materials Cyclooxygenase COX is

2019-07-24

Methods and materials Cyclooxygenase (COX) is the key enzyme required for the conversion of arachidonic Z-WEHD-FMK to prostaglandin, prostacyclins and thromboxanes., , ,

DNA bound Ku proteins recruit DNA PKcs

2019-07-23

DNA-bound Ku proteins recruit DNA-PKcs; and thereby translocate into the duplex by one helical turn, leaving DNA-PKcs near the DNA terminus to assist in tethering the broken ends together [25].

Acknowledgements This work was supported in part by JSPS

2019-07-22

Acknowledgements This work was supported in part by JSPS KAKENHI Grant Number 26292031.

E 64d DDX belongs to the DEAD box family

2019-07-19

DDX3 belongs to the DEAD-box family of proteins, ATP-dependent RNA helicases characterized by the presence of a highly conserved helicase core domain [13].

Enzyme activity loss during the hydrolysis process has tradi

2019-07-18

Enzyme activity loss during the hydrolysis process has traditionally been associated with thermal, mechanical, and/or chemical mechanisms (Okino et al., 2013, Ye et al., 2012, Zhang et al., 2010).

Vincristine Electron transfer pathway Intramolecular or inte

2019-07-17

Electron transfer pathway Intramolecular (or inter-domain) electron transfer (IET) in CDH has been studied in much depth [], and similar IET occurs in CcPDH, from the PQQ cofactor in the AA12 domain to the heme b in the AA8 domain.

Regulation of p via the ubiquitin

2019-07-16

Regulation of p53 via the ubiquitin-proteasome pathway Studies into regulation of p53 via PTM processes that involve phosphorylation, acetylation, ubiquitination, SUMOylation, neddylation, and methylation are being increasingly reported [23], [24].

Effects of estradiol outside the nucleus

2019-07-15

Effects of estradiol outside the nucleus are often mediated by classical estrogen receptors

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2018-07-29