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In summary we investigated the fluoride sensitivity of diffe
2021-06-04

In summary, we investigated the fluoride sensitivity of different S. mutans strains in terms of enolase activity. Lower enolase activity was not always associated with lower S. mutans growth in cultures with NaF. Gene analysis showed that UA130 and NCH105 both have enolase point mutations. Unique am
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Several of the keloid like lesions seen in these individuals
2021-06-04

Several of the keloid-like lesions seen in these individuals were pigmented. It is of potential relevance that genetic variants in DDR1 [MIM: 600408] have been associated with vitiligo, and DDR1 activation is involved when 5,8,11-Eicosatriynoic Acid are attached to collagen-IV fibers. Because DDR1
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br Materials and methods br Statistical
2021-06-04

Materials and methods Statistical analysis All statistical analyses were performed using SPSS software version 20. Protein GSK1838705A data of DNMTs and clinicopathological parameters were collected. Mann-Whitney U Test was used to assess the differential expression of nonparametric data of DN
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pritelivir receptor The CysLT receptor antagonist BayCysLT R
2021-06-03

The CysLT2 receptor antagonist BayCysLT2RA significantly suppressed multiple antigen challenge-induced infiltration of eosinophils and mononuclear pritelivir receptor into the lung, indicating that CysLT2 receptor activation is involved in leukocyte migration. In contrast to the present finding, Ba
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Unlike CRM exportins Cse and
2021-06-03

Unlike CRM1, exportins Cse1 and Xpot lack a C-extension and instead rely primarily on changes in HEAT-repeat conformation and direct Ran-cargo contacts to ensure low cargo-binding affinity in the cytosol and cooperative assembly of the exportin/Ran/cargo complex in the nucleus (Cook et al., 2005, Co
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br Conclusions CK inhibition protects
2021-06-03

Conclusions CK2 inhibition protects young and aging WM function against an ischemic episode by preserving oligodendrocytes and axonal structure by maintaining mitochondrial integrity. CK2 recruits CDK5 and AKT/GSK3ß signaling to mediate WM ischemic injury in a differential spatiotemporal manner s
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br Signaling of DDR receptor
2021-06-03

Signaling of DDR2 receptor and its regulation Being the tyrosine kinase receptor, downstream signaling of DDR2 receptor is initiated by phosphorylation of cytoplasmic tyrosine residue upon ligand binding (Type II collagen) but the authentic facts or detail information of tyrosine phosphorylation
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Cinobufagin In plants SUMOylation has been shown
2021-06-03

In plants, SUMOylation has been shown to modulate plant hormone signaling (Lois et al., 2003, Miura et al., 2009, Conti et al., 2014), root stem cell maintenance (Xu et al., 2013), and responses to abiotic and biotic stress (Lois, 2010). Many of the plant biological processes regulated by SUMOylatio
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ICT is a product of
2021-06-03

ICT is a product of icariin via the metabolism of intestinal bacteria with estrogen-like activities [33]. ICT as a bone-protecting agent can enhance osteoblast differentiation while suppressing osteoclastic differentiation in vitro [19], and stimulate osteogenic differentiation and inhibit adipogene
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am 580 Several functions of FAT have
2021-06-03

Several functions of FAT10 have been suggested. It has been shown that FAT10 binds noncovalently to the mitotic spindle checkpoint protein MAD2 and that this binding might cause chromosome instability in the cancer am 580 overexpressing FAT10 (Liu et al., 1999, Ren et al., 2006). In other studies, o
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In Arabidopsis the quartet qrt mutant enables the
2021-06-03

In Arabidopsis the quartet1 (qrt1) mutant enables the same type of analysis of gametophytes (pollen) in sets of four (tetrads) derived from individual meioses 61., 62.. Pollen tetrads from one accession (Columbia-0) are used to pollinate a second polymorphic accessions (Landsberg erecta) resulting i
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br Results br Discussion Repair by NHEJ implicitly
2021-06-03

Results Discussion Repair by NHEJ implicitly requires the pairing together of broken chromosome ends. A complex of Ku, XRCC4, DNA ligase IV, and XLF (PEC) is necessary and sufficient for this purpose (Reid et al., 2015). Here, we describe dynamic changes in this complex that are triggered by d
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With regard to the DGATs we have found that the
2021-06-02

With regard to the DGATs, we have found that the majority of algal species encode at least one DGAT1, although it appears to be absent from Ostreococcus and Micromonas, as is the case for yeast, S. cerevisiae. More surprising is the presence of multiple DGAT2 genes in algae, with the exception of C.
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Thiamet G The isolation of a proteinaceous
2021-06-02

The isolation of a proteinaceous putative inhibitor of cysteine proteases from the extracts of Y. enterocolitica and E. coli was performed by affinity chromatography on immobilized and inactivated papain (Fig. 7A). Instead of the column variant of this technique (Tsushima et al., 1992), we used a ba
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br Conflict of interest br Acknowledgments
2021-06-02

Conflict of interest Acknowledgments We thank Jianru Zuo (Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China) for providing fbr11-1 seeds. We are grateful to Carol MacKintosh and the DSTT at the University of Dundee (UK) for anti-RD21 antibodies. This
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